上海同濟(jì)大學(xué) 生命科學(xué)與技術(shù)學(xué)院 張曉艷（副教授）導(dǎo)師簡(jiǎn)介

個(gè)人簡(jiǎn)介

2006 －現(xiàn)在：同濟(jì)大學(xué)生命科學(xué)與技術(shù)學(xué)院

2000－2003：復(fù)旦大學(xué)生命科學(xué)學(xué)院植物學(xué)專業(yè)博士生，2003年6月獲理學(xué)博士學(xué)位

1998－1999：美國(guó)密執(zhí)安州立大學(xué)林學(xué)系博士生

1995－1997：美國(guó)新墨西哥州高地大學(xué)生命科學(xué)學(xué)院碩士生，1997年12月獲科學(xué)碩士學(xué)位

1984－2000：中國(guó)科學(xué)院武漢植物研究所

 

主要科研項(xiàng)目：

2012－2014：人乳頭瘤病毒HPV與內(nèi)源性miRNA相互作用模型的建立及其致癌危險(xiǎn)性研究，自然科學(xué)基金（合作申請(qǐng)）

2008－2011：利用小鼠基因剔除技術(shù)發(fā)現(xiàn)新的基因工程藥物，863計(jì)劃 副組長(zhǎng)

2007－2010：建立基于臨床醫(yī)療信息共享平臺(tái)的醫(yī)療決策支持系統(tǒng)，863計(jì)劃 主要參加者

2003－2007：基因功能預(yù)測(cè)的系統(tǒng)發(fā)育分析模型與檢驗(yàn)方法, 973項(xiàng)目 主要參加者

 

近年發(fā)表文章情況：

1． Xin Zhao, Qi Liu, Qingqing Cai, Yanyun Li, Congjian Xu, Yixue Li, Zuofeng Li,*and Xiaoyan Zhang1,* Dr.VIS: a database of human disease-related viral integration sites, Nucl. Acids Res. (2011) Nucleic Acids Research, 2012, Vol. 40, Database issue D1041–D1046（SCI 通訊作者）

2． Zuofeng Li, Xingnan Liu, Jingran Wen,Y, e Xu, Xin Zhao, Xuan Li, Lei Liu*, and Xiaoyan Zhang,* DRUMS: A human disease related unique gene mutation search engine, 2011, HUMAN MUTATION Database in Brief 32: E2259-E2265 (2011) Online （SCI 通訊作者）

3． Yang Yang, Zuofeng Li, Peng Nan, Xiaoyan Zhang*,2011，Drug-induced glucose-6-phosphate dehydrogenase deficiency-related hemolysis risk assessment, Computational Biology and Chemistry 35 (2011) 189–192 (SCI 通訊作者)

4． Wei W.Q., Liu F.Q., Liu L., Li Z.F., Zhang X.Y., Jiang F., Shi Q., Zhou X.Y., Sheng W.Q., Cai S.J., Li X., Xu Y., Nan P. Distinct mutations in MLH1 and MSH2 genes in Hereditary Non-polyposis Colorectal Cancer (HNPCC) families from China. BMB Rep, 2011 May;44(5):317-22. (SCI )

5． Liu Xinyi, Li Zuofeng,Cai Qingqing，Zhang Xiaoyan*. Prediction of multiple drug resistance phenotype in cancer cell lines using gene expression profiles and phylogenetic trees. Chinese Sci Bull, 2010, 55: 3778−3786 （SCI 通訊作者）

6． Xin Zhao, Zoufeng Li, Xiaoyan Zhang*. 2010. G6PD-MutDB: A MUTATION AND PHENOTYPE DATABASE OF GLUCOSE-6-PHOSPHATE (G6PD) DEFICIENCY. Journal of Bioinformatics and Computational Biology. Volume: 8, Supplementary Issue 1(2010) pp. 101-1099

7． Qingqing Cai, Zoufeng Li, Xiaoyan Zhang*. MiRNAs as promising phylogenetic markers for inferring deep metazoan phylogeny and in support of Olfactores hypothesis. BIBM'2010. pp.101~104

8． Qiang Zeng, Xiaoyan Zhang*…., Extracting Clinical Information from Free-text of Pathology and Operation Notes via Chinese Natural Language Processing, 2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops

9． Liu Xinnan, Xu Ye, Li Zuofeng, Liu Lei and Zhang Xiaoyan*，2009，ESCPP: An Evaluation and Alerting System for the Compatibility between Practice Guidelines and Practicing Medicine Using Arden Syntax

10． Wen Jingran, Zhang XIaoyan*, Xu Ye, Li Zuofeng and Liulei, Comparation of AdaBoost and Logistic Regression for Detection Colorectal Cancer Patients with Synchronous Liver Metastasis（ICBPE2009）(EI Accession number:20101612851195)

11． Gong Cheng,1,* Xin Zhao,1,* Zuofeng Li, Xinyi Liu, Weiyao Yan, Xiaoyan Zhang, Yang Zhong, and Zhaoxin Zheng1Identification of a Putative Invertebrate Helical Cytokine Similar to the Ciliary Neurotrophic Factor/Leukemia Inhibitory Factor Family by PSI-BLAST-Based Approach,2009 Journal of Interferon & Cytokine Research,Vol 29(8) 462-468 (SCI ）

12． HAO Pei，YU Yao, ZHANG Xiaoyan, …etc. The contribution of cis-regulatory elements to head-to-head gene pairs’ co-expression pattern, Sci China Ser C-Life Sci Jan.2009,52(1)74-79 (SCI ）